APPLICATION INSTRUCTION OF PHARMACEUTICAL PRODUCT
NEOCOLD
WITH ORANGE, LEMON, HONEY, HONEY AND LEMON OR RASPBERRY FLAVOUR

DRUG FORM: Solution preparing powder in sachets – 7 g.
COMPOSITION OF ONE SACHET: Paracetamol – 500mg, ascorbic acid – 50mg, caffeine – 25mg, mucaltin – 50mg, aloe dry extract – 10mg;
Aiding substances: Sugar, saccharin sodium, lemon acid, sodium citrate, orange, lemon, honey, honey and lemon or raspberry emulsion, raspberry flavour, PEG.
PHARMACOLOGICAL OPERATION: Neocold is a combined preparation, which has antipyretic, perspirative, expectorant, anti-inflammatory, weak pain reliever action. Removes weakness and feeling of fatigue.
Paracetamol characterizes painkilling, temperature lowering, weak anti-inflammatory operation. Acting mechanism is related to the in suppress of prostaglandin synthesis in heat regulation of the hypothalamus.
Ascorbic acid: increases organisms’ stability towards the infection; fills organisms’ requirement on C vitamin at time of acute viral respiratory infection.
Mucaltin: Calms coughing, covers damaged mucous membrane with thin layer, softens and dissolute dense inflammatory scurf (throat, larynx, sound yoga), hastens regeneration of damaged mucous membrane, protects inhalant nerve endings from irritation.
Aloe dry extract: It is characterized with bactericidal, antiviral, anti-inflammatory, antioxidative operation, includes biogenic stimulators.
Caffeine: Reduced feeling of tiredness. At time of headache strengthens operation of paracetamol. At time of infectious diseases mobilizes organisms’ vital forces.
INDICATION: IT IS USED IN COMPLEX THERAPY, AS AN AID MEAN: Symptomatic treatment at the time of influenza and cold, which is characterized with temperature increasing, sneezing, acute rhinitis, headache, sore throat, and muscle ache.
CONTRA INDICATION:
· Additional sensitivity toward the component composing in the preparation.
· Diabetes mellitus.
INTERACTION WITH OTHER DRUGS: Enhances the effect of indirect anticoagulants (coumarin derivatives) and liver damage by hepatotoxic drugs. Metoclopramide increases and Сholestyramine reduces the absorption intensity of the drug. Barbiturates reduce Neocold’s antipyretic effect. Ethyl alcohol accelerates the absorption of paracetamol.
PREGNANCY AND LACTATION PERIOD: Usage the preparation is contraindicated during pregnancy and lactation period. Usage the preparation during lactation period feeding should be stopped.
OVERDOSAGE: In case of overdosage within 24 hours may develop skin pallor, anorexia, nausea, vomiting.
In case of overdosage should stomach lavage, application of adsorbents, acetylcysteine and methionine is recommended.
SIDE EFFECTS: There isn’t a side effect at time of recommended doses. Sometimes allergic reaction are possible, like rash on the skin, itch, Quincke’s edema.
Rarely – disorder on side of hemopoietic system.
In high dosage and long term taking of the preparation may cause functional disorder of the liver and kidney, for that there is necessary blood checking.
SAFETY MEASURES:
· Preparation isn’t recommended at the time of pregnancy and lactation;
· The preparation is safely prescribed in combination with MAO inhibitor and beta-adrenergic blocking agents.
· Neocold is safely prescribed at the time of hard forms of diabetes mellitus, hard functional disorder of internal organs, hyperthyroidism, expressed atherosclerosis of coronary artery.
· It isn’t recommended to use the preparation with other paracetamol composing preparations at the same time.
· At time of treatment with Neocold it isn’t permitted to use sleeping means, tranquilizer and alcohol.
USING RULE AND DOSAGE: The content of the sachet should be dissolved in a glass of hot water by stirring.
In adults: 1 sachet once a day in each 4-6 hours, but not more than 4 times during 24 hours.
Treatment period isn’t recommended more that 5 days.
The preparation is especially effective at the time of revealing first signs of influenza and cold.
PACKAGE: 7g powder in one sachet. 10 sachets in cartoon box.
ISSUE: Pharmaceutical product group – III (without a prescription).
SHELF-LIFE: 2 years.
STORAGE CONDITIONS: Store at 15-25ºC temperature in a dark, dry place and keep away from children.
In case of visual defects and expiry of validity date, the preparation can not be used.
MANUFACTURER: Ltd “Neopharmi”.

12th km, David Agmashenebeli alley, Tbilisi, Georgia.
Tel/Fax: +995 (032) 259-64-46; 259-57-90.